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doi:10.1016/S0003-2697(03)00143-X

Psychoneuroendocrinology , 38 (9), 16981708

Copper Overload, Metallothionein, Ceruloplasmin, and Zinc Deficiencies: The Effects on Methylation and Glutathione Pathways Copper is a vital mineral in the body, playing a crucial role in various biological processes

Circulation 111 , 19992012 (2005)

yet, the depletion of sirtuin 3 (SIRT3) inhibited ferroptosis through modulation of the AMPK-mammalian target of rapamycin (mTOR) signaling pathway and a concomitant promotion in GPX4 levels [81]